Smaller role for pol η?

被引：7

作者：

Dörner, T ^{[1
]}

Lipsky, PE

机构：

[1] Univ Hosp Charite, Dept Med Rheumatol & Clin Immunol, D-10098 Berlin, Germany

[2] NIAMSD, NIH, Bethesda, MD 20892 USA

来源：

NATURE IMMUNOLOGY | 2001年 / 2卷 / 11期

关键词：

D O I：

10.1038/ni1101-982

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：982 / 983

页数：2

共 6 条

[1] Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase ζ [J].

Diaz, M ;

Verkoczy, LK ;

Flajnik, MF ;

Klinman, NR .

JOURNAL OF IMMUNOLOGY, 2001, 167 (01) :327-335

[2]

Dorner T, 1997, J IMMUNOL, V158, P2779

[3]

Dörner T, 1998, EUR J IMMUNOL, V28, P3384

[4] Somatic mutation hotspots correlate with DNA polymerase η error spectrum [J].

Rogozin, IB ;

Pavlov, YI ;

Bebenek, K ;

Matsuda, T ;

Kunkel, TA .

NATURE IMMUNOLOGY, 2001, 2 (06) :530-536

[5] The translesion DNA polymerase ζ plays a major role in Ig and bcl-6 somatic hypermutation [J].

Zan, H ;

Komori, A ;

Li, ZD ;

Cerutti, A ;

Schaffer, A ;

Flajnik, MF ;

Diaz, M ;

Casali, P .

IMMUNITY, 2001, 14 (05) :643-653

[6] DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes [J].

Zeng, XM ;

Winter, DB ;

Kasmer, C ;

Kraemer, KH ;

Lehmann, AR ;

Gearhart, PJ .

NATURE IMMUNOLOGY, 2001, 2 (06) :537-541

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