Rapid and efficient solid phase syntheses of cyclic peptides with endocyclic biaryl ether bonds

被引：55

作者：

Burgess, K ^{[1
]}

Lim, D ^{[1
]}

BoisChoussy, M ^{[1
]}

Zhu, JP ^{[1
]}

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 19期

关键词：

O-G RING; MACROCYCLIZATION REACTION; VANCOMYCIN FAMILY; BIPHENYL ETHER; BINDING POCKET; MODEL; TEICOPLANIN; K-13; ACCESS;

D O I：

10.1016/S0040-4039(97)00654-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Solid phase syntheses of the OF4949 derivatives 1 and 6 - 9 were performed via protection/deprotection of tyrosine side-chains on a support, acid SNAr macrocyclization reactions. (C) 1997 Elsevier Science Ltd.

引用

页码：3345 / 3348

页数：4

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