Gestational vitamin D deficiency: long-term effects on the brain

被引：26

作者：

Levenson, Cathy W. ^{[1
]}

Figueiroa, Silvia M.

机构：

[1] Florida State Univ, Program Neurosci, Tallahassee, FL 32306 USA

来源：

NUTRITION REVIEWS | 2008年 / 66卷 / 12期

关键词：

apoptosis; brain; stem cells; schizophrenia; VDR; vitamin D;

D O I：

10.1111/j.1753-4887.2008.00122.x

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Gestational vitamin D deficiency causes permanent changes in the developing rat brain. Not only does it alter brain gene and protein expression, deficiency disrupts the balance between neuronal stem cell proliferation and programmed cell death in the offspring. These data are particularly relevant in light of new work showing a high prevalence of vitamin D deficiency in humans.

引用

页码：726 / 729

页数：4

共 28 条

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