Target-based discovery of novel herbicides

被引：35

作者：

Lein, W

Börnke, F

Reindl, A

Ehrhardt, T

Stitt, M

Sonnewald, U

机构：

[1] Max Planck Inst Mol Pflanzenphysiol, D-14476 Golm, Germany

[2] Inst Pflanzengenet & Kulturpflanzenforsch, IPK, D-06466 Gatersleben, Germany

[3] BASF AG, Global Res Agr Prod, GVA, HB, D-67056 Ludwigshafen, Germany

来源：

CURRENT OPINION IN PLANT BIOLOGY | 2004年 / 7卷 / 02期

关键词：

D O I：

10.1016/j.pbi.2004.01.001

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In the past 10 years, strategies for the first steps of herbicide discovery have switched from the testing of chemicals for efficacy on whole plants towards the use of in-vitro assays against molecular targets. Many different approaches have been developed to identify bona fide targets for in-vitro screening. Developments in functional genomics and in pharmaceutical research could aid the development of assay systems for the evaluation of chemicals for their suitability as lead structures in herbicide discovery.

引用

页码：219 / 225

页数：7

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