Letter: Radical ion and protonated molecule formation with retinal in electrospray and nanospray

被引：12

作者：

Guaratini, T

Gates, PJ

Cardozo, KHM

Campos, PMBGM

Colepicolo, P

Lopes, NP

机构：

[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP, Brazil

[2] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

来源：

EUROPEAN JOURNAL OF MASS SPECTROMETRY | 2006年 / 12卷 / 01期

关键词：

retinoids; retinal; retinoic acid; nanospray ionisation; electrospray ionisation; molecular ion;

D O I：

10.1255/ejms.784

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

This paper reports a preliminary study of the nanospray ionisation mass spectrometry analyses of retinoic acid and retinal. The results are compared and contrasted to the results normally observed with electrospray ionisation. A significant difference in behaviour was observed for the balance between radical ion formation and protonated molecule formation for retinal. The results suggest that the influence of the very different ionisation conditions present in nanospray is very important in determining how ionisation is achieved and has potentially wide ranging applications in the fields of mass spectral analysis of biological and medical extracts.

引用

页码：71 / 74

页数：4

共 15 条

[1] Superior transduction of mouse hematopoietic stem cells with 10A1 and VSV-G pseudotyped retrovirus vectors [J].