Clinical applications of proton radiation treatment at Loma Linda University: Review of a fifteen-year experience

被引:34
作者
Slater, JD [1 ]
机构
[1] Loma Linda Univ, Dept Radiat Med, Loma Linda, CA 92354 USA
关键词
cancer therapy; conformal radiation therapy; proton; radiotherapy; review;
D O I
10.1177/153303460600500202
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Proton radiation therapy has been used at Loma Linda University Medical Center for 15 years, sometimes in combination with photon irradiation, surgery, and chemotherapy, but often as the sole modality Our initial experience was based on established studies showing the utility of protons for certain management problems, but since then we have engaged in a planned program to exploit the capabilities of proton radiation and expand its applications in accordance with progressively accumulating clinical data. Our cumulative experience has confirmed that protons are a superb tool for delivering conformal radiation treatments, enabling delivery of effective doses of radiation and sparing normal tissues from radiation exposure.
引用
收藏
页码:81 / 89
页数:9
相关论文
共 56 条
[1]   CHARGED-PARTICLE IRRADIATION OF CHORDOMA AND CHONDROSARCOMA OF THE BASE OF SKULL AND CERVICAL-SPINE - THE LAWRENCE-BERKELEY-LABORATORY EXPERIENCE [J].
BERSON, AM ;
CASTRO, JR ;
PETTI, P ;
PHILLIPS, TL ;
GAUGER, GE ;
GUTIN, P ;
COLLIER, JM ;
HENDERSON, SD ;
BAKEN, K .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1988, 15 (03) :559-565
[2]   Effects of proton and combined proton photon beam radiation on pulmonary function in patients with resectable but medically inoperable non-small cell lung cancer [J].
Bonnet, RB ;
Bush, D ;
Cheek, GA ;
Slater, JD ;
Panossian, D ;
Franke, C ;
Slater, JM .
CHEST, 2001, 120 (06) :1803-1810
[3]   High-dose proton beam radiotherapy of hepatocellular carcinoma: Preliminary results of a phase II trial [J].
Bush, DA ;
Hillebrand, DJ ;
Slater, JM ;
Slater, JD .
GASTROENTEROLOGY, 2004, 127 (05) :S189-S193
[4]   Hypofractionated proton beam radiotherapy for stage I lung cancer [J].
Bush, DA ;
Slater, JD ;
Shin, BB ;
Cheek, G ;
Miller, DW ;
Slater, JM .
CHEST, 2004, 126 (04) :1198-1203
[5]   Fractionated proton beam radiotherapy for acoustic neuroma [J].
Bush, DA ;
McAllister, CJ ;
Loredo, LN ;
Johnson, WD ;
Slater, JM ;
Slater, JD .
NEUROSURGERY, 2002, 50 (02) :270-273
[6]   Proton-beam radiotherapy for early-stage lung cancer [J].
Bush, DA ;
Slater, JD ;
Bonnet, R ;
Cheek, GA ;
Dunbar, RD ;
Moyers, M ;
Slater, JM .
CHEST, 1999, 116 (05) :1313-1319
[7]   Pulmonary injury from proton and conventional radiotherapy as revealed by CT [J].
Bush, DA ;
Dunbar, RD ;
Bonnet, R ;
Slater, JD ;
Cheek, GA ;
Slater, JM .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1999, 172 (03) :735-739
[8]   CHORDOMA - THE RESULTS OF MEGAVOLTAGE RADIATION-THERAPY [J].
CUMMINGS, BJ ;
HODSON, DI ;
BUSH, RS .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1983, 9 (05) :633-642
[9]   HEAVY-CHARGED-PARTICLE RADIOSURGERY FOR INTRACRANIAL ARTERIOVENOUS-MALFORMATIONS [J].
FABRIKANT, JI ;
LEVY, RP ;
STEINBERG, GK ;
SILVERBERG, GD ;
FRANKEL, KA ;
PHILLIPS, MH ;
LYMAN, JT .
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 1991, 57 (1-2) :50-63
[10]   CONSERVATIVE SURGERY FOR THE MANAGEMENT OF INVASIVE AND NONINVASIVE CARCINOMA OF THE BREAST - NSABP TRIALS [J].
FISHER, B ;
ANDERSON, S .
WORLD JOURNAL OF SURGERY, 1994, 18 (01) :63-69