Rapid infusion of cold saline (4°C) as adjunctive treatment of fever in patients with brain injury

被引：24

作者：

Badjatia, N

Bodock, M

Rordorf, GA

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Neurobiol, Boston, MA USA

[2] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Pharm, Boston, MA USA

来源：

NEUROLOGY | 2006年 / 66卷 / 11期

关键词：

D O I：

10.1212/01.wnl.0000218166.54150.0a

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The use of rapid infusion of large-volume cold saline ( CS) as an adjunctive therapy for treating refractory fever in nine patients is reported. A decline in temperature (39.2 +/- 0.3 vs 37.1 +/- 1.2 degrees C, p = 0.006) at 2 hours and fever burden (97.3 +/- 343.8 vs 734.3 +/- 422.3 degrees C* min, p = 0.02) at 12 hours was noted after CS bolus. Rapid infusion of large-volume CS may be used as an adjunct for inducing normothermia in refractory febrile patients.

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页码：1739 / 1741

页数：3

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