Short report:: Failure of standard treatment with praziquantel in two returned travelers with Schistosoma haematobium infection

被引：105

作者：

Alonso, D

Muñoz, J

Gascón, J

Valls, ME

Corachan, M

机构：

[1] Hosp Clin Barcelona, Inst Invest Biomed August Pi & Sunyer, Int Hlth Ctr, Ctr Diagnost Biomed Clin, Barcelona, Spain

[2] Hosp Clin Barcelona, Inst Invest Biomed August Pi & Sunyer, Microbiol Serv, Ctr Diagnost Biomed Clin, Barcelona, Spain

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2006年 / 74卷 / 02期

关键词：

D O I：

10.4269/ajtmh.2006.74.342

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A single 40 mg/kg dose of praziquantel (PZQ) continues to be the standard treatment for schistosomiasis caused by S. mansoni and S. haematobium in all clinical settings. Experimental development of drug resistance and the recent isolation of S. mansoni strains with a natural tolerance to high doses of PZQ have raised concerns over the adequacy of such a dose. We describe two Spanish travelers with genitourinary schistosomiasis caused by S. haematobium in whom repeated standard treatment failed to clear the infection.

引用

页码：342 / 344

页数：3

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