Complete circular DNA genome of a TT virus variant (isolate name SANBAN) and 44 partial ORF2 sequences implicating a great degree of diversity beyond genotypes

被引：117

作者：

Hijikata, M ^{[1
]}

Takahashi, K ^{[1
]}

Mishiro, S ^{[1
]}

机构：

[1] Toshiba Gen Hosp, Dept Med Sci, Shinagawa Ku, Tokyo 1408522, Japan

来源：

VIROLOGY | 1999年 / 260卷 / 01期

关键词：

TT virus (TTV); chicken anemia virus (CAV); chicken infectious anemia virus; (CIAV); Circoviridae; Circinoviridae; single-stranded circular DNA virus; genetic diversity;

D O I：

10.1006/viro.1999.9797

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Information on the entire genome of TT Virus (TTV) has been scarce. The circular ssDNA genome of a variant (isolate name SANBAN) that we sequenced was only 56.7% homologous to the prototype isolate (TA278), with even lower homology at the amino acid level: 34.2% for ORF1 and 39.7% for ORF2. Regarding the ORF1, SANBAN was only very distantly related to the six major TTV genotypes reported to date. In partial ORF2 sequences determined on 44 isolates taken together, TTV has a broad range of genetic diversity and the SANBAN isolate may represent a new TTV-like viral species or genus and not merely a genotype of TTV. (C) 1999 Academic Press.

引用

页码：17 / 22

页数：6

共 19 条

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