Structure of the respiratory NADH:ubiquinone oxidoreductase (complex I)

被引：81

作者：

Grigorieff, N ^{[1
]}

机构：

[1] Brandeis Univ, Rosenstiel Basic Med Sci Res Ctr, WM Keck Inst Cellular Visualizat, Waltham, MA 02454 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1999年 / 9卷 / 04期

关键词：

D O I：

10.1016/S0959-440X(99)80067-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three-dimensional structures of NADH:ubiquinone oxidoreductase (or complex I) from the respiratory chain of mitochondria and bacteria have been recently studied by electron microscopy. The low-resolution structures all reveal a characteristic L shape for complex I; however, some of the differences among these structures may have important implications for the location of the functional elements of complex I, for example, the ubiquinone-binding site.

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页码：476 / 483

页数：8

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