Palladium-catalyzed carbonylation and coupling reactions of aryl chlorides and amines

被引：50

作者：

Perry, RJ ^{[1
]}

Wilson, BD ^{[1
]}

机构：

[1] EASTMAN KODAK CO,IMAGING RES & ADV DEV,ROCHESTER,NY 14650

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 21期

关键词：

D O I：

10.1021/jo960861j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium-catalyzed amidation of electron-deficient aryl chlorides proceeds readily in the presence of low CO pressures and a slight excess of an iodide salt, The rates of amidation are accelerated over those without added salt, and iodide is preferred over bromide or chloride, More electron-rich aryl chlorides were not effectively amidated, either with or without added iodide. We postulate that an intermediate anionic palladium(0) iodide complex is responsible for the enhanced reactivity.

引用

页码：7482 / 7485

页数：4

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