Spermatogenic ability is different among males in different Y chromosome lineage

被引：83

作者：

Kuroki, Y

Iwamoto, T

Lee, JW

Yoshiike, M

Nozawa, S

Nishida, T

Ewis, AA

Nakamura, H

Toda, T

Tokunaga, K

Kotliarova, SE

Kondoh, N

Koh, E

Namiki, M

Shinka, T

Nakahori, Y

机构：

[1] Univ Tokushima, Sch Med, Dept Publ Hlth, Tokushima 7708503, Japan

[2] St Marianna Univ, Sch Med, Dept Urol, Kawasaki, Kanagawa, Japan

[3] Univ Tokyo, Grad Sch Med, Dept Human Genet, Tokyo, Japan

[4] Osaka Cent Hosp, Dept Urol, Osaka, Japan

[5] Kanazawa Univ, Sch Med, Dept Urol, Kanazawa, Ishikawa 920, Japan

来源：

JOURNAL OF HUMAN GENETICS | 1999年 / 44卷 / 05期

关键词：

sperm concentration; azoospermia; spermatogenic ability; Y chromosome; haplotype; male lineage;

D O I：

10.1007/s100380050162

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

It is a controversial question whether sperm concentrations in humans are changing, Several researchers have reported on environmental factors affecting sperm quality, but the influence of genetic factors is still not fully understood. In this study, we examined the relationship between Y chromosome haplotypes and sperm concentration in fertile males. In addition, we determined the haplotypes of azoospermic patients. The results show that the mean sperm concentration correlates with Y chromosome type. Moreover, the occurrence of azoospermia is related to one particular Y chromosome lineage. Thus, males with a certain haplotype are at a disadvantage for fathering children. The difference of spermatogenic ability among men is important not only in pursuing male competition as in the past but also as relates to the future of modern human males.

引用

页码：289 / 292

页数：4

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