Development and evaluation of a rapid dipstick assay for serodiagnosis of acute human brucellosis

被引：32

作者：

Smits, HL

Basahi, MA

Díaz, R

Marrodan, T

Douglas, JT

Rocha, A

Veerman, J

Zheludkov, MM

Witte, OWM

de Jong, J

Gussenhoven, GC

Goris, MGA

van der Hoorn, MAWG

机构：

[1] Royal Trop Inst, Dept Biomed Res, NL-1105 AZ Amsterdam, Netherlands

[2] Med Sans Frontieres, Amsterdam, Netherlands

[3] DLO, Inst Anim Sci & Hlth, Dept Microbiol, Lelystad, Netherlands

[4] Yhoc Sanaa Med Labs, Sanaa, Yemen

[5] Univ Navarra, Dept Clin Microbiol, E-31080 Pamplona, Spain

[6] Univ Hawaii, Dept Microbiol, Honolulu, HI 96822 USA

[7] Inst Nacl Saude, Lisbon, Portugal

[8] NF Gamaleya Epidemiol & Microbiol Res Inst, Moscow, Russia

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1999年 / 37卷 / 12期

关键词：

D O I：

10.1128/JCM.37.12.4179-4182.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A dipstick assay for the detection of brucella-specific immunoglobulin M antibodies was evaluated with 707 sera from 247 laboratory-confirmed brucellosis patients and 342 control sera from brucellosis-free individuals. These sera were collected from six different countries. The assay was found to be highly sensitive and specific. In addition, the test is easy to use and does not require specialized training or equipment, and the components are stable without a requirement for refrigeration. ALI of these factors make the test ideal for developing countries and rural settings.

引用

页码：4179 / 4182

页数：4

共 26 条

[1] Seroprevalence of brucellosis among high risk people in northern Jordan [J].