Bloinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments

被引：323

作者：

Mano, JF

Sousa, RA

Boesel, LF

Neves, NM

Reis, RL

机构：

[1] Univ Minho, Dept Polymer Engn, P-4800058 Guimaraes, Portugal

[2] Univ Minho, Res Grp 3Bs, P-4710057 Braga, Portugal

来源：

COMPOSITES SCIENCE AND TECHNOLOGY | 2004年 / 64卷 / 06期

关键词：

biomaterials; polymer matrix composites; mechanical properties; microstructures; injection moulding;

D O I：

10.1016/j.compscitech.2003.09.001

中图分类号：

TB33 [复合材料];

学科分类号：

摘要：

The present review paper examines the use of different types of polymeric matrix composites in hard tissue replacement applications. The review presents the actual state of the art in the fields of bioinert composites for permanent applications, biodegradable matrix composites for temporary applications and the emerging area of injectable composites. In all cases some recent developments are also discussed. The paper starts with an introduction to locate the reader. Bone-analogue composites are then extensively discussed. Several other systems based on an inert polymeric matrix are described, focusing on their proposed applications. A great emphasis is afterwards given to biodegradable matrix systems. The most widely used synthetic bioresorbable systems are analysed and compared with an example of natural origin degradable composites-starch based composites. Finally, composite systems that are non-processable by melt based routes and in many cases injectable are discussed in detail, including several recent developments on this emerging area of research. (C) 2003 Published by Elsevier Ltd.

引用

页码：789 / 817

页数：29

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