Pheromone-inducible conjugation in Enterococcus faecalis:: A model for the evolution of biological complexity?

被引：35

作者：

Kozlowicz, BK ^{[1
]}

Dworkin, M ^{[1
]}

Dunny, GM ^{[1
]}

机构：

[1] Univ Minnesota, Sch Med, Dept Microbiol, Minneapolis, MN 55455 USA

来源：

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY | 2006年 / 296卷 / 2-3期

关键词：

peptide signal molecule; horizontal gene transfer; genetic regulation;

D O I：

10.1016/j.ijmm.2006.01.040

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Pheromone-inducible transfer of the plasmid pCF10 in Enterococcus faecalis is regulated using a complicated network of proteins and RNAs. The plasmid itself has been assembled from parts garnered from a variety of sources, and many aspects of the system resemble a biological kluge. Recently several new functions of various pCF10 gene products that participate in regulation of plasmid transfer have been identified. The results indicate that selective pressures controlling the evolution of the plasmid have produced a highly complex regulatory network with multiple biological functions that may serve well as a model for the evolution of biological complexity. (c) 2006 Elsevier GmbH. All rights reserved.

引用

页码：141 / 147

页数：7

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