Keratolimbal allograft: Recommendations for tissue procurement and preparation by eye banks, and standard surgical technique

Purpose. To facilitate increased use of keratolimbal allograft transplantation (KLAL) for severe ocular surface disease (OSD) by informing clinicians and eye banks of differences in tissue requirements and preparation for the procedure and to describe the surgical technique of KLAL transplantation. Methods. The protocol of the Minnesota Lions Eye Bank is described for procuring and preparing tissue for KLAL transplantation. The surgical technique is described in detail. Results. Over the last several years, we have modified our eye-banking procedures as well as our surgical technique to improve the success of KLAL transplantation. Conclusion, KLAL transplantation for patients with severe ocular-surface disease is an important management option. Success is influenced by the ability to obtain appropriate tissue; this requires clinicians and eye banks to expand current procurement guidelines.