Virus resistance and gene silencing: killing the messenger

被引：88

作者：

Waterhouse, PM ^{[1
]}

Smith, NA ^{[1
]}

Wang, MB ^{[1
]}

机构：

[1] CSIRO, Canberra, ACT 2601, Australia

来源：

TRENDS IN PLANT SCIENCE | 1999年 / 4卷 / 11期

关键词：

D O I：

10.1016/S1360-1385(99)01493-4

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

On occassion, virus-derived transgenes in plants can be poorly expressed and yet provide excellent virus resistance, and transgene constructs designed to supplement the expression of endogenous genes can have the effect of co-suppressing themselves and the endogenous genes. These two phenomena appear to result from the same poet-transcriptional silencing mechanism, which operates by targeted-RMA degradation. Recent research into RNA-mediated virus resistance and co-suppression has provided insights into the interactions between plant Viruses and their hosts, and spawned several models to explain the phenomenon.

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页码：452 / 457

页数：6

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