Disseminated toxoplasmosis, resulting from infection of allograft, after orthotopic liver transplantation: Usefulness of quantitative PCR

被引:42
作者
Botterel, F
Ichai, P
Feray, C
Bourec, P
Saliba, F
Raspa, RT
Samuel, D
Romand, S
机构
[1] Univ Paris 11, Parasitol & Mycol Dept, Hop Bicetre, Microbiol Serv,Fac Med Paris Sud, F-94275 Le Kremlin Bicetre, France
[2] Hop Paul Brousse, Ctr Hepatobiliaire, F-94804 Villejuif, France
[3] Inst Puericulture, F-75014 Paris, France
[4] Rabin Med Ctr, Liver Unit, Tel Aviv, Israel
关键词
D O I
10.1128/JCM.40.5.1648-1650.2002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Disseminated toxoplasmosis is a life-threatening disease in liver transplant recipients that can result from an organ-transmitted infection. We report here a case of fatal disseminated toxoplasmosis after orthotopic liver transplantation from a seropositive donor (immunoglobulin G [IgG](+) and IgM(-)) in a patient who was nonimmune for toxoplasmosis prior to transplantation. Quantitative PCR analyses of various clinical specimens, including serum samples, appeared retrospectively to be a valuable diagnostic tool that might guide therapeutic attitudes.
引用
收藏
页码:1648 / 1650
页数:3
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