Lymphocyte infusion for delayed extramedullary relapse of acute leukemia following bone marrow transplantation

被引:15
作者
Fleming, DR
Greenwood, MF
Garrison, J
Geil, JD
Romond, EH
机构
[1] Markey Cancer Center, Department of Medicine, University of Kentucky Markey Cancer Center, Lexington, KY
[2] Department of Pediatrics, Divisions of Hematology/Oncology, University of Kentucky Markey Cancer Center, Lexington, KY
[3] Department of Medicine, Division of Hematology/Oncology, University of Kentucky, Markey Cancer Center, Lexington, KY 40536-0093
关键词
acute myelogenous leukemia; donor lymphocyte infusion; extramedullary; relapse; allogeneic bone marrow transplantation;
D O I
10.3109/10428199609093456
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We report a case of extramedullary relapse of acute myelogenous leukemia twelve years after allogeneic bone marrow transplantation. Due to the localized nature of the relapse, we were able to eliminate a majority of the tumor burden, utilizing local irradiation. Destined with eventual systemic leukemia relapse, further therapy utilizing donor lymphocytes was given at a time of minimal disease burden. The patient remains in a state of complete remission.
引用
收藏
页码:525 / 528
页数:4
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