A robust approach to extract biomedical events from literature

被引:21
作者
Bui, Quoc-Chinh [1 ]
Sloot, Peter M. A. [1 ]
机构
[1] Univ Amsterdam, Fac Sci, Inst Informat, NL-1012 WX Amsterdam, Netherlands
关键词
DRUG-DRUG INTERACTIONS;
D O I
10.1093/bioinformatics/bts487
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: The abundance of biomedical literature has attracted significant interest in novel methods to automatically extract biomedical relations from the literature. Until recently, most research was focused on extracting binary relations such as protein-protein interactions and drug-disease relations. However, these binary relations cannot fully represent the original biomedical data. Therefore, there is a need for methods that can extract fine-grained and complex relations known as biomedical events. Results: In this article we propose a novel method to extract biomedical events from text. Our method consists of two phases. In the first phase, training data are mapped into structured representations. Based on that, templates are used to extract rules automatically. In the second phase, extraction methods are developed to process the obtained rules. When evaluated against the Genia event extraction abstract and full-text test datasets (Task 1), we obtain results with F-scores of 52.34 and 53.34, respectively, which are comparable to the state-of-the-art systems. Furthermore, our system achieves superior performance in terms of computational efficiency.
引用
收藏
页码:2654 / 2661
页数:8
相关论文
共 30 条
  • [1] Event extraction for systems biology by text mining the literature
    Ananiadou, Sophia
    Pyysalo, Sampo
    Tsujii, Jun'ichi
    Kell, Douglas B.
    [J]. TRENDS IN BIOTECHNOLOGY, 2010, 28 (07) : 381 - 390
  • [2] [Anonymous], 2011, P 2011 C EMPIRICAL M
  • [3] [Anonymous], 2011, P BIONLP SHAR TASK 2
  • [4] [Anonymous], 2011, P BIONLP SHARED TASK
  • [5] Bjorne J., 2011, P BIONLP SHARED TASK, P183
  • [6] Bjorne J., 2009, P WORKSH CURR TRENDS, P10
  • [7] Complex event extraction at PubMed scale
    Bjorne, Jari
    Ginter, Filip
    Pyysalo, Sampo
    Tsujii, Jun'ichi
    Salakoski, Tapio
    [J]. BIOINFORMATICS, 2010, 26 (12) : i382 - i390
  • [8] Bui Q.C., 2011, BioNLP Shared Task 2011 Workshop, P143
  • [9] Extracting causal relations on HIV drug resistance from literature
    Bui, Quoc-Chinh
    Nuallain, Breanndan O.
    Boucher, Charles A.
    Sloot, Peter M. A.
    [J]. BMC BIOINFORMATICS, 2010, 11
  • [10] Buyko E., 2009, P WORKSHOP CURRENT T, P19