Structural features and mechanisms for sensing high osmolarity in microorganisms

被引：16

作者：

Heermann, R ^{[1
]}

Jung, K ^{[1
]}

机构：

[1] Tech Univ Darmstadt, Inst Microbiol & Genet, D-64287 Darmstadt, Germany

来源：

CURRENT OPINION IN MICROBIOLOGY | 2004年 / 7卷 / 02期

关键词：

D O I：

10.1016/j.mib.2004.02.008

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

During their lifetime, most organisms experience osmotic stress, mostly due to fluctuating external osmolarities, but also as a result of desiccation or freezing. Under these conditions, the ratio of osmolytes to water and macromolecules in the cells is significantly altered. To survive, cells must continuously sense these alterations and adapt accordingly. Osmolarity is a physico-chemical parameter that causes pleiotropic alterations in cell physiology. Recent research has revealed various mechanisms to sense high external osmolarity, based on monitoring cellular changes that are associated with the altered environment.

引用

页码：168 / 174

页数：7

共 46 条

[1] Identification of OpuC as a chill-activated and osmotically activated carnitine transporter in Listeria monocytogenes [J].

Angelidis, AS ;

Smith, LT ;

Hoffman, LM ;

Smith, GM .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2002, 68 (06) :2644-2650

[2] Probing conservation of HAMP linker structure and signal transduction mechanism through analysis of hybrid sensor kinases [J].

Appleman, JA ;

Chen, LL ;

Stewart, V .

JOURNAL OF BACTERIOLOGY, 2003, 185 (16) :4872-4882

[3] Potassium uptake in the unicellular cyanobacterium Synechocystis sp strain PCC 6803 mainly depends on a Ktr-like system encoded by slr1509 (ntpJ) [J].

Berry, S ;

Esper, B ;

Karandashova, I ;

Teuber, M ;

Elanskaya, I ;

Rögner, M ;

Hagemann, M .

FEBS LETTERS, 2003, 548 (1-3) :53-58

[4] Modulation of KdpD phosphatase implicated in the physiological expression of the Kdp ATPase of Escherichia coli [J].

Brandon, L ;

Dorus, S ;

Epstein, W ;

Altendorf, K ;

Jung, K .

MOLECULAR MICROBIOLOGY, 2000, 38 (05) :1086-1092

[5]

Culham DE, 2000, J MOL RECOGNIT, V13, P309, DOI 10.1002/1099-1352(200009/10)13:5<309::AID-JMR505>3.3.CO

[6]

2-I

[7] Osmosensor ProP of Escherichia coli responds to the concentration, chemistry, and molecular size of osmolytes in the proteoliposome lumen [J].

Culham, DE ;

Henderson, J ;

Crane, RA ;

Wood, JM .

BIOCHEMISTRY, 2003, 42 (02) :410-420

[8] The roles and regulation of potassium in bacteria [J].

Epstein, W .

PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 75, 2003, 75 :293-320

[9]

Galperin MY, 2001, FEMS MICROBIOL LETT, V203, P11, DOI 10.1111/j.1574-6968.2001.tb10814.x

[10] The N-terminal input domain of the sensor kinase KdpD of Escherichia coli stabilizes the interaction between the cognate response regulator KdpE and the corresponding DNA-binding site [J].

Heermann, R ;

Altendorf, K ;

Jung, K .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (51) :51277-51284

← 1 2 3 4 5 →