Tacrolimus clinical studies for atopic dermatitis and other conditions

被引:20
作者
Bergman, J
Rico, MJ
机构
[1] Fujisawa Healthcare Inc, Deerfield, IL 60015 USA
[2] Childrens Hosp, Div Pediat & Adolescent Dermatol, San Diego, CA USA
[3] NYU, Dept Dermatol, New York, NY 10016 USA
关键词
D O I
10.1053/sder.2001.29061
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The first topical immunomodulator approved for human use, tacrolimus ointment (Protopic, Fujisawa, Healthcare, Inc, Deerfield, IL), has been shown to be effective and safe In the treatment of children (aged 2 years and older) and adults with atopic dermatitis (AD). Clinical trials conducted worldwide have involved 12,000 patients, with safety and efficacy data available for up to 3 years of treatment. In addition to its beneficial effects in the management of AD, topical tacrolimus has also been reported to be of benefit in other immunologically mediated skin diseases including: hand dermatitis, contact dermatitis, eyelid dermatitis, erosive lichen planus, steroid-induced rosacea, pyoderma gangrenosum, and graft-versus-host disease. This article reviews the clinical experience of topical tacrolimus in the treatment of AD and other skin conditions. Copyright (C) 2001 by W.B. Saunders Company.
引用
收藏
页码:250 / 259
页数:10
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