Arterial dimensions in the lower extremities of patients with abdominal aortic aneurysms -: no indications of a generalized dilating diathesis

被引:35
作者
Sandgren, T [1 ]
Sonesson, B
Ryden-Ahlgren, Å
Länne, T
机构
[1] Lund Univ, Malmo Univ Hosp, Dept Surg, MAS, S-20502 Malmo, Sweden
[2] Lund Univ, Malmo Univ Hosp, Dept Vasc Dis, S-20502 Malmo, Sweden
[3] Lund Univ, Malmo Univ Hosp, Dept Clin Physiol, S-20502 Malmo, Sweden
[4] Linkoping Univ, Div Vasc Surg, Jonkoping, Sweden
关键词
D O I
10.1067/mva.2001.119399
中图分类号
R61 [外科手术学];
学科分类号
摘要
Purpose: This study assessed whether there is a dilating diathesis in peripheral arteries,of patients with abdominal aortic aneurysms (AAAs). Methods. The anteroposterior diameters of the common femoral artery (CPA) and popliteal artery (PA) were measured in 183 consecutive patients with an AAA (158 men, 25 women; age range, 57-78 years) before elective surgery on the AAA and compared with that of healthy age-matched control subjects. The diameter registrations were performed on the right leg by using a noninvasive echo-tracking ultrasound scanning technique. Results: Eight CIA aneurysms and four PA aneurysms were found in the male patients with AAAs. Of the patients with AAAs in the CIA and in the PA who were investigated, 46% and 49%, respectively, were affected by peripheral vascular occlusive disease (PVOD). The CFA diameters in the patients with AAAs were 97.8% of those in healthy control subjects (P = not significant [NS]). After exclusion of the CIA aneurysms, the diameters were 92.7% of those in healthy control subjects (P =.0003). If patients with PVOD were also excluded, the CFA diameters were 95.2% of those in healthy control subjects (P =.022). The PA diameters in the patients with AAAs were 97.8% of those in healthy control subjects (P = NS). If PA aneurysms were excluded, the diameters were 94.4% of those in healthy control subjects (P =.0003). If patients with PVOD were also excluded, the PA diameters were 96.1% of those in healthy control subjects (P = NS). Conclusion: After excluding the few patients with AAAs who had peripheral aneurysmal disease and the patients with PVOD, no dilating diathesis in CFAs and PAs was found. This supports the hypothesis that specific genetic, or other factors, not present in most AAAs are responsible for the occurrence of concomitant peripheral aneurysms. Furthermore, the generalized vascular dilating diathesis seen in some patients seems to be a specific entity that was not necessarily affiliated with AAA disease.
引用
收藏
页码:1079 / 1084
页数:6
相关论文
共 37 条
  • [1] ABDOMINAL AORTIC-ANEURYSMS ARE ASSOCIATED WITH ALTERED MATRIX PROTEINS OF THE NONANEURYSMAL AORTIC SEGMENTS
    BAXTER, BT
    DAVIS, VA
    MINION, DJ
    WANG, YP
    LYNCH, TG
    MCMANUS, BM
    [J]. JOURNAL OF VASCULAR SURGERY, 1994, 19 (05) : 797 - 803
  • [2] ARTERIAL ALTERATIONS WITH AGING AND HIGH BLOOD-PRESSURE - A NONINVASIVE STUDY OF CAROTID AND FEMORAL ARTERIES
    BENETOS, A
    LAURENT, S
    HOEKS, AP
    BOUTOUYRIE, PH
    SAFAR, ME
    [J]. ARTERIOSCLEROSIS AND THROMBOSIS, 1993, 13 (01): : 90 - 97
  • [3] Bengtsson H, 1991, Eur J Vasc Surg, V5, P53
  • [4] BOUTOUYRIE P, 1992, J HYPERTENS, V10, pS87
  • [5] Brophy C M, 1991, Ann Vasc Surg, V5, P229, DOI 10.1007/BF02329378
  • [6] A DEFINITION OF ARTERIOMEGALY AND THE SIZE OF ARTERIES SUPPLYING THE LOWER-LIMBS
    CALLUM, KG
    THOMAS, ML
    BROWSE, NL
    [J]. BRITISH JOURNAL OF SURGERY, 1983, 70 (09) : 524 - 529
  • [7] THE INCIDENCE OF POPLITEAL ANEURYSMS IN PATIENTS WITH ARTERIOMEGALY
    CHAN, O
    THOMAS, ML
    [J]. CLINICAL RADIOLOGY, 1990, 41 (03) : 185 - 189
  • [8] Dawson I, 1997, BRIT J SURG, V84, P293
  • [9] Incidence of femoral and popliteal artery aneurysms in patients with abdominal aortic aneurysms
    Diwan, A
    Sarkar, R
    Stanley, JC
    Zelenock, GB
    Wakefield, TW
    [J]. JOURNAL OF VASCULAR SURGERY, 2000, 31 (05) : 863 - 869
  • [10] INFLAMMATION AND MATRIX METALLOPROTEINASES IN THE ENLARGING ABDOMINAL AORTIC-ANEURYSM
    FREESTONE, T
    TURNER, RJ
    COADY, A
    HIGMAN, DJ
    GREENHALGH, RM
    POWELL, JT
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1995, 15 (08) : 1145 - 1151