Diastereoselective elaboration of 2,3,4-substituted piperidines using diene iron tricarbonyl complexes. Total synthesis of (+/-)-dienomycin C and (+/-)-4-epi-dienomycin C

被引：18

作者：

Ripoche, I ^{[1
]}

Bennis, K ^{[1
]}

Canet, JL ^{[1
]}

Gelas, J ^{[1
]}

Troin, Y ^{[1
]}

机构：

[1] UNIV CLERMONT FERRAND,ENSCCF,LAB CHIM HETEROCYCLES & GLUCIDES,F-63174 CLERMONT FERRAN,FRANCE

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 23期

关键词：

D O I：

10.1016/0040-4039(96)00621-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The diastereoselective formation of 2,3,4-substituted piperidines is achieved by condensation of the iron dienal complex 2 and the primary amine 3 via an intramolecular Mannich-type cyclisation. This method is illustrated by the first total synthesis of (+/-)-dienomycin C 1 and its C-4 epimer 9. (C) 1996 Elsevier Science Ltd

引用

页码：3991 / 3992

页数：2

共 8 条

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