Biomimetic surface modifications based on the cyanobacterial iron chelator anachelin

被引：122

作者：

Zürcher, S

Wäckerlin, D

Bethuel, Y

Malisova, B

Textor, M

Tosatti, S

Gademann, K

机构：

[1] Surface Solut GmbH, Surface Sci & Technol Lab, Dept Mat, CH-8093 Zurich, Switzerland

[2] ETH, Organ Chem Lab, Dept Chem & Appl Biosci, CH-8093 Zurich, Switzerland

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 04期

关键词：

D O I：

10.1021/ja056256s

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Siderophores are natural iron chelators that have been evolutionarily selected to bind to Fe ions with very high binding constants. We utilize these unique properties to bind to metal oxide surfaces using a fragment of the cyanobacterial siderophore anachelin. The resulting poly(ethylene glycol) conjugate forms stable adlayers on TiO2 as has been shown by variable angle spectroscopic ellipsometry and X-ray photoelectron spectroscopy. Moreover, these coated surfaces are highly protein-resistant against the adsorption of full human serum. Copyright © 2006 American Chemical Society.

引用

页码：1064 / 1065

页数：2

共 26 条

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