Has advice on periconceptional folate supplementation reduced neural-tube defects?

被引：26

作者：

Abramsky, L

Botting, B

Chapple, J

Stone, D

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Sch Med, Dept Med & Community Genet, London SW7 2AZ, England

[2] Univ London Imperial Coll Sci Technol & Med, Sch Med, Natl Congenital Anomaly Syst, Off Natl Stat, London SW7 2AZ, England

[3] Univ London Imperial Coll Sci Technol & Med, Sch Med, Dept Epidemiol & Publ Hlth, London SW7 2AZ, England

[4] Univ Glasgow, Dept Child Hlth, Paediat Epidemiol & Community Hlth Unit, Glasgow G12 8QQ, Lanark, Scotland

来源：

LANCET | 1999年 / 354卷 / 9183期

关键词：

D O I：

10.1016/S0140-6736(99)03248-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Periconceptional folate supplementation has been encouraged in the UK since the early 1990s, but no concurrent decline in neural-tube-defect pregnancies has been observed by regional congenital anomaly registers.

引用

页码：998 / 999

页数：2

共 5 条

[1] PREVENTION OF THE 1ST OCCURRENCE OF NEURAL-TUBE DEFECTS BY PERICONCEPTIONAL VITAMIN SUPPLEMENTATION [J].

CZEIZEL, AE ;

DUDAS, I .

NEW ENGLAND JOURNAL OF MEDICINE, 1992, 327 (26) :1832-1835

[2]

OWENS JR, 1981, LANCET, V2, P1032

[3] APPARENT PREVENTION OF NEURAL-TUBE DEFECTS BY PERICONCEPTIONAL VITAMIN SUPPLEMENTATION [J].

SMITHELLS, RW ;

SHEPPARD, S ;

SCHORAH, CJ ;

SELLER, MJ ;

NEVIN, NC ;

HARRIS, R ;

READ, AP ;

FIELDING, DW .

ARCHIVES OF DISEASE IN CHILDHOOD, 1981, 56 (12) :911-918

[4]

STONE DH, 1987, DEV MED CHILD NEUROL, V29, P541

[5]

WALD N, 1991, LANCET, V338, P131

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