Molecular genetics of extranodal marginal zone (MALT-type) B-cell lymphoma

被引：12

作者：

Bertoni, F ^{[1
]}

Cotter, FE ^{[1
]}

Zucca, E ^{[1
]}

机构：

[1] Osped San Giovanni Bellinzona, Serv Oncol Cantonale, CH-6500 Bellinzona, Switzerland

来源：

LEUKEMIA & LYMPHOMA | 1999年 / 35卷 / 1-2期

基金：

美国国家科学基金会;

关键词：

molecular biology; marginal zone lymphoma; MALT; extranodal lymphoma; gastric; PCR;

D O I：

10.3109/10428199909145705

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mucosa-associated lymphoid tissue lymphoma is now classified as extranodal marginal zone B-cell lymphoma. We reviewed the current literature on the biological and genetic mechanisms that lead to the development and progression of this unusual lymphoma. Particular attention was given to the clinical and biological significance of the immunoglobulin genes rearrangement, that has been proposed and widely used both diagnostically and as a tool to monitor the response to antibiotic treatment.

引用

页码：57 / 68

页数：12

共 108 条

[1] VH gene analysis of primary cutaneous B-cell lymphomas: Evidence for ongoing somatic hypermutation and isotype switching [J].

Aarts, WM ;

Willemze, R ;

Bende, RJ ;

Meijer, CJLM ;

Pals, ST ;

van Noesel, CJM .

BLOOD, 1998, 92 (10) :3857-3864

[2]

[Anonymous], 1996, ADV IMMUNOLOGY

[3] Death receptors: Signaling and modulation [J].

Ashkenazi, A ;

Dixit, VM .

SCIENCE, 1998, 281 (5381) :1305-1308

[4] t(11;18)(q21;q21) is the most common translocation in MALT lymphomas [J].

Auer, IA ;

Gascoyne, RD ;

Connors, JM ;

Cotter, FE ;

Greiner, TC ;

Sanger, WG ;

Horsman, DE .

ANNALS OF ONCOLOGY, 1997, 8 (10) :979-985

[5] Ongoing Ig gene hypermutation in salivary gland mucosa-associated lymphoid tissue-type lymphomas [J].

Bahler, DW ;

Miklos, JA ;

Swerdlow, SH .

BLOOD, 1997, 89 (09) :3335-3344

[6] Clonal salivary gland infiltrates associated with myoepithelial sialadenitis (Sjogren's syndrome) begin as nonmalignant antigen-selected expansions [J].

Bahler, DW ;

Swerdlow, SH .

BLOOD, 1998, 91 (06) :1864-1872

[7] Treatment and prognosis in a series of primary extranodal lymphomas of the ocular adnexa [J].

Baldini, L ;

Blini, M ;

Guffanti, A ;

Fossati, V ;

Colombi, M ;

La Targia, ML ;

Bertoni, F ;

Alietti, A ;

Neri, A ;

Bertoni, G .

ANNALS OF ONCOLOGY, 1998, 9 (07) :779-781

[8] Characteristic pattern of chromosomal gains and losses in primary large B-cell lymphomas of the gastrointestinal tract [J].

Barth, TFE ;

Döhner, H ;

Werner, CA ;

Stilgenbauer, S ;

Schlotter, M ;

Pawlita, M ;

Lichter, P ;

Möller, P ;

Bentz, M .

BLOOD, 1998, 91 (11) :4321-4330

[9] Immunoglobulin heavy chain diversity genes rearrangement pattern indicates that MALT-type gastric lymphoma B cells have undergone an antigen selection process [J].

Bertoni, F ;

Cazzaniga, G ;

Bosshard, G ;

Roggero, E ;

Barbazza, R ;

DeBoni, M ;

Capella, C ;

Pedrinis, E ;

Cavalli, F ;

Biondi, A ;

Zucca, E .

BRITISH JOURNAL OF HAEMATOLOGY, 1997, 97 (04) :830-836

[10]

Brynes RK, 1996, MODERN PATHOL, V9, P995

← 1 2 3 4 5 6 7 8 9 10 →