Age and sex effects on brain morphology

被引：84

作者：

Passe, TJ

Rajagopalan, P

Tupler, LA

Byrum, CE

MacFall, JR

Krishnan, KRR

机构：

[1] DUKE UNIV,MED CTR,DEPT PSYCHIAT,DURHAM,NC 27710

[2] DUKE UNIV,MED CTR,DEPT RADIOL,DURHAM,NC 27710

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 1997年 / 21卷 / 08期

关键词：

age; gray matter; magnetic resonance imaging; sex differences; white matter;

D O I：

10.1016/S0278-5846(97)00160-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

1. Brain morphology can be assessed readily in vivo using magnetic resonance imaging (MRI). 2. In this study, the effects of age and sex on whole-brain morphology were examined using an operator-controlled computer-segmentation protocol. 3. Results indicated that age was associated with gray-matter volume reduction. 4. Brain-size differences between males and females were primarily attributable to white-matter volume. 5. This study confirms the importance of controlling for age and sex in brain-morphology studies.

引用

页码：1231 / 1237

页数：7

共 17 条

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