Asymmetry and immune memory

被引：8

作者：

Littman, Dan R.

Singh, Harinder

机构：

[1] NYU, Howard Hughes Med Inst, Skirball Inst Biomol Med, New York, NY 10016 USA

[2] Univ Chicago, Howard Hughes Med Inst, Dept Mol Genet & Cell Biol, Chicago, IL 60637 USA

来源：

SCIENCE | 2007年 / 315卷 / 5819期

关键词：

D O I：

10.1126/science.1141184

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Asymmetric cell division of lymphocytes ensures that our adaptive immune system maintains a balanced production of two different types of T cells.

引用

页码：1673 / 1674

页数：2

共 13 条

[1] Dare to be different:: Asymmetric cell division in Drosophila, C-elegans and vertebrates [J].

Betschinger, J ;

Knoblich, JA .

CURRENT BIOLOGY, 2004, 14 (16) :R674-R685

[2] Asymmetric T lymphocyte division in the initiation of adaptive immune responses [J].

Chang, John T. ;

Palanivel, Vikram R. ;

Kinjyo, Ichiko ;

Schambach, Felix ;

Intlekofer, Andrew M. ;

Banerjee, Arnob ;

Longworth, Sarah A. ;

Vinup, Kristine E. ;

Mrass, Paul ;

Oliaro, Jane ;

Killeen, Nigel ;

Orange, Jordan S. ;

Russell, Sarah M. ;

Weninger, Wolfgang ;

Reiner, Steven L. .

SCIENCE, 2007, 315 (5819) :1687-1691

[3] The distal pole complex: a novel membrane domain distal to the immunological synapse [J].

Cullinan, P ;

Sperling, AI ;

Burkhardt, JK .

IMMUNOLOGICAL REVIEWS, 2002, 189 :111-122

[4] Signaling takes shape in the immune system [J].

Dustin, ML ;

Chan, AC .

CELL, 2000, 103 (02) :283-294

[5]

Fuerstenberg S, 1998, INT J DEV BIOL, V42, P379

[6] The Immunological Synapse: A Molecular Machine Controlling T Cell Activation [J].

Grakoui, Arash ;

Bromley, Shannon K. ;

Sumen, Cenk ;

Davis, Mark M. ;

Shaw, Andrey S. ;

Allen, Paul M. ;

Dustin, Michael L. .

JOURNAL OF IMMUNOLOGY, 2015, 194 (09) :221-227

[7] Immunology - CD8 T cells remember with a little help [J].

Kaech, SM ;

Ahmed, R .

SCIENCE, 2003, 300 (5617) :263-265

[8] Differentiation of memory B and T cells [J].

Kalia, Vandana ;

Sarkar, Surojit ;

Gourley, Tania S. ;

Rouse, Barry T. ;

Ahmed, Rafi .

CURRENT OPINION IN IMMUNOLOGY, 2006, 18 (03) :255-264

[9] Asymmetric cell divisions promote stratification and differentiation of mammalian skin [J].

Lechler, T ;

Fuchs, E .

NATURE, 2005, 437 (7056) :275-280

[10] Three-dimensional segregation of supramolecular activation clusters in T cells [J].

Monks, CRF ;

Freiberg, BA ;

Kupfer, H ;

Sciaky, N ;

Kupfer, A .

NATURE, 1998, 395 (6697) :82-86

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