Polygenic detection of Rickettsia felis in cat fleas (Ctenocephalides felis) from Israel

被引：20

作者：

Bauer, O

Baneth, G

Eshkol, T

Shaw, SE

Harrus, S

机构：

[1] Hebrew Univ Jerusalem, Sch Vet Med, IL-76100 Rehovot, Israel

[2] Let Anim Live Assoc, Talmei Menashe, Israel

[3] Univ Bristol, Dept Vet Clin Sci, Langford, Somerset, England

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2006年 / 74卷 / 03期

关键词：

D O I：

10.4269/ajtmh.2006.74.444

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The presence of Rickettsia felis, an emerging bacterial pathogen, was investigated in 79 cat flea (Cteno-cephalides felis) pools from Israel (5 to 20 fleas each) by polymerase chain reaction (PCR) and sequencing of 5 different genes. Amplified targets included both metabolic (gltA and fusA) and surface antigen (ompA, ompB, and the 17-kDa antigen) genes. R. felis DNA was detected in 7.6% of the flea pools. Two genotypes similar in their housekeeping gene sequences but markedly different in their surface antigenic genetic milieus were characterized. This is the first detection of this flea-transmitted rickettsia within its vector in Israel and the Middle East. Although no clinical case has been reported in human beings in Israel to date, these findings suggest that this infection is prevalent in Israel.

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收藏

页码：444 / 448

页数：5

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