Gata2 and Gata3:: novel markers for early embryonic polarity and for nonneural ectoderm in the chick embryo

被引：77

作者：

Sheng, GJ ^{[1
]}

Stern, CD ^{[1
]}

机构：

[1] Columbia Univ, Dept Genet & Dev, New York, NY 10032 USA

来源：

MECHANISMS OF DEVELOPMENT | 1999年 / 87卷 / 1-2期

关键词：

Gata2; Gata3; epidermis; non-neural ectoderm; intermediate mesoderm; embryonic polarity;

D O I：

10.1016/S0925-4773(99)00150-1

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We have investigated in detail the expression patterns of two Gata genes, cGata2 and cGata3, during early chick development. In addition to confirming previously described expression of these two genes in developing brain, kidney and blood islands, this study reveals several important novel expression domains during very early stages of development. cGata2 is expressed in the area opaca in pre-primitive streak stages, forming a gradient along the A-P axis (strongest anteriorly). Both genes are expressed strongly in the entire non-neural ectoderm, from stage 4+, and neither is expressed in prospective neural plate at any stage. Unlike other previously described non-neural markers, neither gene is expressed in the dorsal neural tube. We also describe dynamic expression of cGata2 and cGata3 during eye, ear and gut development. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：213 / 216

页数：4

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