A novel method to produce hydroxyapatite objects with interconnecting porosity that avoids sintering

被引：121

作者：

Tadic, D

Beckmann, F

Schwarz, K

Epple, M ^{[1
]}

机构：

[1] Univ Duisburg Essen, Inst Inorgan Chem, D-45117 Essen, Germany

[2] DESY, HASYLAB, D-22607 Hamburg, Germany

[3] GKSS Forschungszentrum Geesthacht GmbH, D-21502 Geesthacht, Germany

来源：

BIOMATERIALS | 2004年 / 25卷 / 16期

关键词：

porosity; polyvinylalcohol (PVA); apatite; bone substitution; micro-computer tomography;

D O I：

10.1016/j.biomaterials.2003.10.007

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Porous objects of carbonated apatite were prepared by mixing polyvinyl alcohol fibres (PVA) and sodium chloride as porogens with nanocrystalline carbonated apatite powder. After cold isostatic pressing (CIP) and dissolving the porogens, the bioceramic showed an interconnecting porosity with pore diameters in the range of 250-400 mum. The method can be transposed to any material that is insoluble in water (like many polymers). Such objects are promising for bone regeneration because the interconnecting porosity in carbonated apatite provides a good environment for bone attachment and ingrowth. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：3335 / 3340

页数：6

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