Viruses and their uses in nanotechnology

被引:124
作者
Singh, Pratik [1 ]
Gonzalez, Maria J. [1 ]
Manchester, Marianne [1 ]
机构
[1] Scripps Res Inst, Ctr Integrat Mol Biosci, Dept Cell Biol, La Jolla, CA 92037 USA
关键词
virus; VLP; nanoparticles; nanotechnology Al47823 vertical bar CA112075 vertical bar NOI-CO27181;
D O I
10.1002/ddr.20064
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The use of materials derived from natural sources in materials science has allowed the harnessing of complex structures resulting from eons of evolutionary fine-tuning. A better understanding of the structure and function of viruses has revealed a collection of natural molecular assemblies and containers with a variety of shapes, sizes, stabilities, dynamic properties, and chemical reactivities. Viruses are increasingly being used in materials science, engineering, and nanotechnology as tools and building blocks for electronics, chemistry, and biomedical science. Here we discuss different types of viruses presently in use, their physical properties, and their potential uses in a variety of nanotechnology applications.
引用
收藏
页码:23 / 41
页数:19
相关论文
共 179 条
[1]   Efficient intracellular delivery of a protein and a low molecular weight substance via recombinant polyomavirus-like particles [J].
Abbing, A ;
Blaschke, UK ;
Grein, S ;
Kretschmar, M ;
Stark, CMB ;
Thies, MJW ;
Walter, J ;
Weigand, M ;
Woith, DC ;
Hess, J ;
Reiser, COA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (26) :27410-27421
[2]   Bromovirus RNA replication and transcription [J].
Ahlquist, Paul .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 1992, 2 (01) :71-76
[3]   Therapeutic cancer targeting peptides [J].
Aina, OH ;
Sroka, TC ;
Chen, ML ;
Lam, KS .
BIOPOLYMERS, 2002, 66 (03) :184-199
[4]   Comparative analysis of integrin expression on monocyte-derived macrophages and monocyte-derived dendritic cells [J].
Ammon, C ;
Meyer, SP ;
Schwarzfischer, L ;
Krause, SW ;
Andreesen, R ;
Kreutz, M .
IMMUNOLOGY, 2000, 100 (03) :364-369
[5]   Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model [J].
Arap, W ;
Pasqualini, R ;
Ruoslahti, E .
SCIENCE, 1998, 279 (5349) :377-380
[6]   Targeting the prostate for destruction through a vascular address [J].
Arap, W ;
Haedicke, W ;
Bernasconi, M ;
Kain, R ;
Rajotte, D ;
Krajewski, S ;
Ellerby, HM ;
Bredesen, DE ;
Pasqualini, R ;
Ruoslahti, E .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (03) :1527-1531
[7]  
Arap Wadih, 1998, Current Opinion in Oncology, V10, P560, DOI 10.1097/00001622-199811000-00014
[8]   Nano-tailoring: Stitching alterations on viral coats [J].
Arora, PS ;
Kirshenbaum, K .
CHEMISTRY & BIOLOGY, 2004, 11 (04) :418-420
[9]   Contrasting roles of endosomal pH and the cytoskeleton in infection of human glial cells by JC virus and simian virus 40 [J].
Ashok, A ;
Atwood, WJ .
JOURNAL OF VIROLOGY, 2003, 77 (02) :1347-1356
[10]   Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells [J].
Atkinson, SF ;
Bettinger, T ;
Seymour, LW ;
Behr, JP ;
Ward, CM .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (30) :27930-27935