Ethical issues in genetic research: Disclosure and informed consent

被引：72

作者：

Reilly, PR ^{[1
]}

Boshar, MF ^{[1
]}

Holtzman, SH ^{[1
]}

机构：

[1] MILLENNIUM PHARMACEUT INC,CAMBRIDGE,MA 02139

来源：

NATURE GENETICS | 1997年 / 15卷 / 01期

关键词：

D O I：

10.1038/ng0197-16

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

As research to correlate genetic status with predisposition to disease has accelerated, so has the concern that participation in such studies creates the risk of genetic discrimination and emotional distress. There is a need to broaden disclosure during the consent process to ensure that potential subjects understand these risks and other issues and to address them in the consent form. We describe the broad approach that we have taken in regard to disclosure and consent in gene mapping studies.

引用

页码：16 / 20

页数：5

共 18 条

[1]

*AAAS DIR SCI POL, 1993, C ETH LEG ASP PED RE

[2]

*AM SOC HUM GEN, 1994, AM J HUM GENET, V55, pR1

[3]

*AM SOC HUM GEN, 1996, AM J HUM GENET, V59, P471

[4]

*AM SOC HUM GEN BO, 1995, AM J HUM GENET, V57, P1233

[5]

[Anonymous], 1994, RADON RENTAL HOUSING

[6] GENETIC-COUNSELING FOR FAMILIES WITH INHERITED SUSCEPTIBILITY TO BREAST AND OVARIAN-CANCER [J].

BIESECKER, BB ;

BOEHNKE, M ;

CALZONE, K ;

MARKEL, DS ;

GARBER, JE ;

COLLINS, FS ;

WEBER, BL .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1993, 269 (15) :1970-1974

[7]

BLATT R, 1993, GENET RESOUR, V7, P32

[8]

BLOCH M, 1990, AM J HUM GENET, V46, P1

[9] INFORMED CONSENT FOR GENETIC RESEARCH ON STORED TISSUE SAMPLES [J].

CLAYTON, EW ;

STEINBERG, KK ;

KHOURY, MJ ;

THOMSON, E ;

ANDREWS, L ;

KAHN, MJE ;

KOPELMAN, LM ;

WEISS, JO .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1995, 274 (22) :1786-1792

[10]

EARLEY CL, 1995, AM J HUM GENET, V57, P727

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