The combined value of chemoprophylaxis and pneumococcal vaccine in the prevention of recurrent pneumococcal meningitis

被引：10

作者：

Hristea, A ^{[1
]}

Chiotan, M ^{[1
]}

Tudose, M ^{[1
]}

Mihalcu, F ^{[1
]}

机构：

[1] CANTACUZINO INST MICROBIOL,BUCHAREST,ROMANIA

来源：

JOURNAL OF INFECTION | 1997年 / 34卷 / 03期

关键词：

D O I：

10.1016/S0163-4453(97)94451-0

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report the case of an immunocompetent patient who has been the subject of 39 episodes of recurrent pneumococcal meningitis over a 20 year period. The recurrences of bacterial meningitis due to cerebrospinal fluid leakage and the presence of chronic sinusitis were not influenced by the surgical repair of a fistula and the repeated surgical draining interventions on suppurating chronic sinusital foci. Phenoxymethylpenicillin treatment reduced the number of recurrences and the combination of pneumococcal vaccine and penicillin prophylaxis allowed a 5 year period free of any recurrences.

引用

页码：265 / 267

页数：3

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