Outline of Occupational Chromium Poisoning in China

被引：54

作者：

Yang, Yuan ^{[1
,2
]}

Liu, Hong ^{[1
]}

Xiang, Xian-hong ^{[3
]}

Liu, Fu-you ^{[1
]}

机构：

[1] Cent S Univ, Xiangya Hosp 2, Postdoctoral Res Stn, Inst Nephrol, Changsha 410011, Hunan, Peoples R China

[2] Huaihua Med Coll, Dept Clin Lab, Huaihua 418000, Hunan, Peoples R China

[3] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Intervent Radiol, Guangzhou 510080, Guangdong, Peoples R China

来源：

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY | 2013年 / 90卷 / 06期

关键词：

Occupational chromium poisoning; Epidemiological characteristics; China; HEXAVALENT CHROMIUM; OXIDATIVE STRESS; CANCER-MORTALITY; DRINKING-WATER; TOXICITY; CARCINOGENICITY; METALS; MECHANISMS; EXPOSURE;

D O I：

10.1007/s00128-013-0998-3

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The present study analyzed the feature of occupational chromium poisoning in China since the 1980s. The collected data were acquired from 18 previous surveys of chromium poisoning in 14 cities of China. The method of risk assessment was applied to calculate the relative risk and 95 % CI, p < 0.05 was considered as a significant risk. The results showed that nasal disease was the most common sign of occupational chromium poisoning, and the prevalence rate of nasal disease was 17.83 % in total population of 6,998. Further, the risk analysis showed that occupational chromium poisoning led to an increased risk of lung or liver cancer in male workers due to the definite carcinogenicity of hexavalent chromium. Significantly, an increased risk of spontaneous or threatened abortion was also found in female workers. In conclusion, these studies suggest that early detection of impaired reproductive function or impaired lung or liver function in female or male workers is essential for controlling occupational chromium poisoning in China.

引用

页码：742 / 749

页数：8

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