Spinocerebellar ataxia type 2 presenting as familial levodopa-responsive parkinsonism

被引：76

作者：

Shan, DE ^{[1
]}

Soong, BW

Sun, CM

Lee, SJ

Liao, KK

Liu, RS

机构：

[1] Taipei Vet Gen Hosp, Inst Neurol, Taipei 11217, Taiwan

[2] Taipei Vet Gen Hosp, Natl PET Cyclotron Ctr, Taipei 11217, Taiwan

[3] Natl Yang Ming Univ, Dept Neurol, Taipei 112, Taiwan

[4] Natl Yang Ming Univ, Dept Phys Therapy, Taipei 112, Taiwan

来源：

ANNALS OF NEUROLOGY | 2001年 / 50卷 / 06期

关键词：

D O I：

10.1002/ana.10055

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A genetic analysis identified 2 patients, approximately one-tenth of our patients with familial parkinsonism, who had expanded trinucleotide repeats in SCA2 genes. The reduction of F-18-dopa distribution in both the putamen and caudate nuclei confirmed that the nigrostriatal dopaminergic system was involved in parkinsonian patients with SCA2 mutation.

引用

页码：812 / 815

页数：4

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