Copper-Nitrene Complexes in Catalytic C-H Amination

被引：284

作者：

Badiei, Yosra M. ^{[2
]}

Dinescu, Adriana ^{[1
]}

Dai, Xiliang ^{[2
]}

Palomino, Robert M. ^{[2
]}

Heinemann, Frank W. ^{[3
]}

Cundari, Thomas R. ^{[1
]}

Warren, Timothy H. ^{[2
]}

机构：

[1] Univ N Texas, CASCaM, Dept Chem, Denton, TX 78203 USA

[2] Georgetown Univ, Dept Chem, Washington, DC 20057 USA

[3] Univ Erlangen Nurnberg, Dept Chem & Pharm, Erlangen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 51期

基金：

美国国家科学基金会;

关键词：

amination; C-H activation; copper; density functional calculations; nitrenes;

D O I：

10.1002/anie.200804304

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Hydrocarbons activate! Isolable β-diketiminato dicopper-nitrene complexes such as 1 derived from the reaction of [{(Cl2NN)Cu}2(μ-benzene)] and 1-adamantylazide are potent towards nitrene insertion into unactivated sp 3-hybridized C-H bonds. 1 allows stoichiometric and catalytic intermolecular C-H amination of hydrocarbons to give secondary amines (see scheme). Catalyst loadings as low as 0.05 mol% may be used. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：9961 / 9964

页数：4

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