A new approach to Hmb-backbone protection of peptides: Synthesis and reactivity of N-alpha-Fmoc-N-alpha-(Hmb)amino acids

被引：26

作者：

Nicolas, E

Pujades, M

Bacardit, J

Giralt, E

Albericio, F

机构：

[1] Dept. de Quimica Orgànica, Universitat de Barcelona, E-08028 Barcelona, Marti i Franquès

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 13期

关键词：

D O I：

10.1016/S0040-4039(97)00303-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of N-Fmoc-N-(Hmb)amino acids for the introduction of the Hmb backbone protection into peptides during solid-phase synthesis is described An efficient two step synthesis of these derivatives is reported and their coupling to the peptide chain is studied. (C) 1997 Elsevier Science Ltd.

引用

页码：2317 / 2320

页数：4

共 26 条

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