Structure, conformation, and mechanism in the membrane transport of alkali metal ions by ionophoric antibiotics

被引：59

作者：

Riddell, FG ^{[1
]}

机构：

[1] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland

来源：

CHIRALITY | 2002年 / 14卷 / 2-3期

关键词：

ionophoric antibiotic; membrane transport; NMR spectroscopy;

D O I：

10.1002/chir.10052

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Recent progress in studies of the mechanism of transport of alkali metal ions by ionophoric antibiotics and the structures of alkali metal salts of the ionophores monensin and narasin is reviewed. The structures obtained from 2D NMR experiments in solution provide considerable insights into the mechanisms of transport. (C) 2002 Wiley-Liss, Inc.

引用

页码：121 / 125

页数：5

共 25 条

[1] CONFORMATIONAL-ANALYSIS .25. CONFORMATIONAL EQUILIBRIA IN 5-HETEROSUBSTITUTED 1,3-DIOXANES - COMPARISON OF CALCULATED AND EXPERIMENTAL SOLVENT EFFECTS
ABRAHAM, RJ
BANKS, HD
HOFER, O
KALOUSTI.MK
ELIEL, EL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1972, 94 (06) : 1913 - &
[2] SODIUM COMPLEX OF THE MONOHYDRATED IONOPHORE MONENSIN-B
BARRANS, Y
ALLEAUME, M
JEMINET, G
[J]. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1982, 38 (APR): : 1144 - 1149
[3] COMPLEXATION OF METAL-IONS BY MONENSIN - CRYSTAL AND MOLECULAR-STRUCTURE OF HYDRATED AND ANHYDROUS CRYSTAL FORMS OF SODIUM MONENSIN
DUAX, WL
SMITH, GD
STRONG, PD
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (22) : 6725 - 6729
[4] Eliel E. L., 1971, PURE APPL CHEM, V25, P509
[5] CONFORMATIONAL-ANALYSIS .37. GAUCHE-REPULSIVE INTERACTIONS IN 5-METHOXY-1,3-DITHIANES AND 5-METHYLTHIO-1,3-DITHIANES
ELIEL, EL
JUARISTI, E
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (19) : 6114 - 6119
[6] CONFORMATIONAL ANALYSIS .16. 1,3-DIOXANES
ELIEL, EL
KNOEBER, MC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (13) : 3444 - &
[7] CONFORMATIONAL ANALYSIS IN SATURATED HETEROCYCLIC COMPOUNDS
ELIEL, EL
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1970, 3 (01) : 1 - &
[8] The conformations of narasin-metal complexes in solution determined by NMR spectroscopy
Martinek, T
Riddell, FG
Wilson, CF
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 2000, (11): : 2192 - 2198
[9] The conformations of monensin-A metal complexes in solution determined by NMR spectroscopy
Martinek, T
Riddell, FG
Wilson, C
Weller, CT
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 2000, (01): : 35 - 41
[10] A MODEL FOR ION-TRANSPORT ACROSS MEMBRANES - SOLUTION STRUCTURE OF THE IONOPHORE METAL-COMPLEX SALINOMYCIN-NA DETERMINED BY NMR AND MOLECULAR-DYNAMICS CALCULATIONS
MRONGA, S
MULLER, G
FISCHER, J
RIDDELL, F
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (18) : 8414 - 8420

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