Fungal peroxidases: molecular aspects and applications

被引：130

作者：

Conesa, A ^{[1
]}

Punt, PJ ^{[1
]}

van den Hondel, CAMJJ ^{[1
]}

机构：

[1] TNO, Nutr & Food Res Inst, Dept Appl Microbiol & Gene Technol, NL-3704 HE Zeist, Netherlands

来源：

JOURNAL OF BIOTECHNOLOGY | 2002年 / 93卷 / 02期

关键词：

fungal peroxidases; white-rot; chloroperoxidase; haem; structure-function relationship; molecular genetics; protein homology; protein structure; heterologous protein production;

D O I：

10.1016/S0168-1656(01)00394-7

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Peroxidases are oxidoreductases that utilize hydrogen peroxide to catalyze oxidative reactions. A large number of peroxidases have been identified in fungal species and are being characterized at the molecular level. In this manuscript we review the current knowledge on the molecular aspects of this type of enzymes. We present an overview of the research efforts undertaken in deciphering the structural basis of the catalytic properties of fungal peroxidases and discuss molecular genetics and protein homology aspects of this enzyme class. Finally, we summarize the potential biotechnological applications of these enzymes and evaluate recent advances on their expression in heterologous systems for production purposes. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：143 / 158

页数：16

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