Why have organelles retained genomes?

被引:175
作者
Race, HL
Herrmann, RG
Martin, W
机构
[1] Univ Munich, Inst Bot, D-8000 Munich, Germany
[2] Tech Univ Carolo Wilhelmina Braunschweig, Inst Genet, D-38023 Braunschweig, Germany
关键词
D O I
10.1016/S0168-9525(99)01766-7
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The observation that chloroplasts and mitochondria have retained relies of eubacterial genomes and a protein-synthesizing machinery has long puzzled biologists. If most genes have been transferred from organelles to the nucleus during evolution, why not all? What selective pressure maintains genomes in organelles? Electron transport through the photosynthetic and respiratory membranes is a powerful - hut dangerous - source of energy. Recent evidence suggests that organelle genomes have persisted because structural proteins that maintain redox balance within bioenergetic membranes must be synthesized when and where they are needed, to counteract the potentially deadly side effects of ATP-generating electron transport.
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页码:364 / 370
页数:7
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