Intracellular amino acid concentrations in children with chronic renal insufficiency

被引：1

作者：

Echten, JEKV ^{[1
]}

Huijmans, JGM ^{[1
]}

Hop, WCJ ^{[1
]}

Monnens, LAH ^{[1
]}

deJong, MCJW ^{[1
]}

Noordzij, CM ^{[1
]}

Slotema, R ^{[1
]}

Nauta, J ^{[1
]}

Wolff, ED ^{[1
]}

机构：

[1] UNIV ROTTERDAM HOSP,SOPHIA CHILDRENS HOSP,DEPT PEDIAT,SUBDIV NEPHROL,ROTTERDAM,NETHERLANDS

来源：

PEDIATRIC NEPHROLOGY | 1996年 / 10卷 / 01期

关键词：

chronic renal failure; granulocytes; amino acids; protein restriction;

D O I：

10.1007/BF00863441

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We studied amino acid concentrations in granulocytes and plasma of 24 children with chronic renal failure and 15 healthy children. Granulocytes were isolated from 10 mi of blood using a dextran-Ficoll-Hypaque procedure. Intracellular levels of leucine, isoleucine, methionine, phenylalanine, lysine, histidine, tyrosine, and arginine were significantly lower in children with chronic renal failure than healthy children. There were no significant differences in intracellular and plasma amino acid concentrations between children with chronic renal failure on a well-balanced protein-restricted diet and children with chronic renal failure with a normal protein intake.

引用

页码：46 / 50

页数：5

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