Extrapolating from Animals to Humans

被引：87

作者：

Ioannidis, John P. A. ^{[1
,2
,3
]}

机构：

[1] Stanford Univ, Dept Med, Stanford Prevent Res Ctr, Sch Med, Stanford, CA 94305 USA

[2] Stanford Univ, Dept Hlth Res & Policy, Sch Med, Stanford, CA 94305 USA

[3] Stanford Univ, Dept Stat, Sch Humanities & Sci, Stanford, CA 94305 USA

来源：

SCIENCE TRANSLATIONAL MEDICINE | 2012年 / 4卷 / 151期

关键词：

STROKE; DESIGN;

D O I：

10.1126/scitranslmed.3004631

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Because of a variety of caveats, the safety and effectiveness of interventions in human subjects can only be speculated from animal studies. Careful synthesis of data from multiple animal studies is needed to begin to assess the likelihood of successful cross-species translation (Fay et al., this issue).

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