Trial sequential analysis has the potential to improve the reliability of conclusions in meta-analysis

被引:14
作者
Imberger, Georgina [1 ]
Wetterslev, Jorn [1 ]
Gluud, Chistian [1 ]
机构
[1] Copenhagen Univ Hosp, Copenhagen Trial Unit, Ctr Clin Intervent Res, Copenhagen O, Denmark
关键词
INFORMATION SIZE; INSUFFICIENT; RISK;
D O I
10.1016/j.cct.2013.07.008
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
100103 [病原生物学]; 100218 [急诊医学];
摘要
引用
收藏
页码:254 / 255
页数:2
相关论文
共 9 条
[1]
Apparently conclusive meta-analyses may be inconclusive-Trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses [J].
Brok, Jesper ;
Thorlund, Kristian ;
Wetterslev, Jorn ;
Gluud, Christian .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2009, 38 (01) :287-298
[2]
Trial sequential analysis reveals insufficient information size and potentially false positive results in many meta-analyses [J].
Brok, Jesper ;
Thorlund, Kristian ;
Gluud, Christian ;
Wetterslev, Jorn .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2008, 61 (08) :763-769
[3]
Casassus P, 2001, BRIT J HAEMATOL, V113, P1020
[4]
Optimal information size in trial sequential analysis of time-to-event outcomes reveals potentially inconclusive results because of the risk of random error [J].
Miladinovic, Branko ;
Mhaskar, Rahul ;
Hozo, Iztok ;
Kumar, Ambuj ;
Mahony, Helen ;
Djulbegovic, Benjamin .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2013, 66 (06) :654-659
[5]
Trial sequential analysis may be insufficient to draw firm conclusions regarding statistically significant treatment differences using observed intervention effects: A case study of meta-analyses of multiple myeloma trials [J].
Miladinovic, Branko ;
Kumar, Ambuj ;
Hozo, Iztok ;
Mahony, Helen ;
Djulbegovic, Benjamin .
CONTEMPORARY CLINICAL TRIALS, 2013, 34 (02) :257-261
[6]
Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses? [J].
Thorlund, Kristian ;
Devereaux, P. J. ;
Wetterslev, Jorn ;
Guyatt, Gordon ;
Ioannidis, John P. A. ;
Thabane, Lehana ;
Gluud, Lise-Lotte ;
Als-Nielsen, Bodil ;
Gluud, Christian .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2009, 38 (01) :276-286
[7]
Evolution of Heterogeneity (I2) Estimates and Their 95% Confidence Intervals in Large Meta-Analyses [J].
Thorlund, Kristian ;
Imberger, Georgina ;
Johnston, Bradley C. ;
Walsh, Michael ;
Awad, Tahany ;
Thabane, Lehana ;
Gluud, Christian ;
Devereaux, P. J. ;
Wetterslev, Jorn .
PLOS ONE, 2012, 7 (07)
[8]
Predicting the extent of heterogeneity in meta-analysis, using empirical data from the Cochrane Database of Systematic Reviews [J].
Turner, Rebecca M. ;
Davey, Jonathan ;
Clarke, Mike J. ;
Thompson, Simon G. ;
Higgins, Julian P. T. .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2012, 41 (03) :818-827
[9]
Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis [J].
Wetterslev, Jorn ;
Thorlund, Kristian ;
Brok, Jesper ;
Gluud, Christian .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2008, 61 (01) :64-75