Analysis of lipophilic antioxidants in human serum and tissues: tocopherols and carotenoids

被引：70

作者：

Aust, O ^{[1
]}

Sies, H ^{[1
]}

Stahl, W ^{[1
]}

Polidori, MC ^{[1
]}

机构：

[1] Univ Dusseldorf, Inst Physiol Chem 1, D-40225 Dusseldorf, Germany

来源：

JOURNAL OF CHROMATOGRAPHY A | 2001年 / 936卷 / 1-2期

关键词：

reviews; antioxidants; tocopherols; carotenoids; vitamins;

D O I：

10.1016/S0021-9673(01)01269-9

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Tocopherols and carotenoids are naturally occurring lipophilic micronutrients, suggested to play a role in the prevention of several degenerative diseases. Thus, methods for the quantification of these nutrients in human samples have been developed during recent years. Blood and tissue levels of tocopherols and carotenoids are influenced by a variety of parameters related to disease, age, diet and lifestyle. This review summarizes general aspects of chromatographic analysis of tocopherols and carotenoids in human samples and deals with information on the outcome of human studies, in which such measurements were applied. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：83 / 93

页数：11

共 103 条

[1]

[Anonymous], 2000, DIETARY REFERENCE IN

[2] Authentication of vegetable oils by chromatographic techniques [J].

Aparicio, R ;

Aparicio-Ruíz, R .

JOURNAL OF CHROMATOGRAPHY A, 2000, 881 (1-2) :93-104

[3] DETECTION AND LOCALIZATION OF LIPID-PEROXIDATION IN SELENIUM-DEFICIENT AND VITAMIN-E-DEFICIENT RATS USING F-2-ISOPROSTANES [J].

AWAD, JA ;

MORROW, JD ;

HILL, KE ;

ROBERTS, LJ ;

BURK, RF .

JOURNAL OF NUTRITION, 1994, 124 (06) :810-816

[4]

BARUA AB, 1992, METHOD ENZYMOL, V213, P273

[5] Synthesis and characterization of extended length alkyl stationary phases for liquid chromatography with application to the separation of carotenoid isomers [J].

Bell, CM ;

Sander, LC ;

Fetzer, JC ;

Wise, SA .

JOURNAL OF CHROMATOGRAPHY A, 1996, 753 (01) :37-45

[6] Lipid peroxidation and antioxidant defenses in cystic fibrosis patients [J].

Benabdeslam, H ;

Abidi, H ;

Garcia, I ;

Bellon, G ;

Gilly, R ;

Revol, A .

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 1999, 37 (05) :511-516

[7] DETERMINATION OF INDIVIDUAL CAROTENOIDS IN HUMAN-PLASMA BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

BIERI, JG ;

BROWN, ED ;

SMITH, JC .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1985, 8 (03) :473-484

[8]

Bone RA, 2001, INVEST OPHTH VIS SCI, V42, P235

[9]

Britton G., 1995, Carotenoids: Spectroscopy, V1B, P13

[10] PLASMA CAROTENOIDS IN NORMAL MEN AFTER A SINGLE INGESTION OF VEGETABLES OR PURIFIED BETA-CAROTENE [J].

BROWN, ED ;

MICOZZI, MS ;

CRAFT, NE ;

BIERI, JG ;

BEECHER, G ;

EDWARDS, BK ;

ROSE, A ;

TAYLOR, PR ;

SMITH, JC .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 1989, 49 (06) :1258-1265

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