Total synthesis of 12-epi-PGF(2 alpha)

被引：40

作者：

Hwang, SW

Adiyaman, M

Khanapure, SP

Rokach, J

机构：

[1] FLORIDA INST TECHNOL,CLAUDE PEPPER INST,MELBOURNE,FL 32901

[2] FLORIDA INST TECHNOL,DEPT CHEM,MELBOURNE,FL 32901

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 06期

关键词：

D O I：

10.1016/0040-4039(95)02390-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel synthesis of 12-epi-PGF(2 alpha) 5 is described. The key synthon 11, which has been used as a starting point for the synthesis, is produced by a radical cyclization process using thionocarbonate 9a. The radical cyclization of 9a to 11 has been studied in some detail.

引用

页码：779 / 782

页数：4

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