Yop fusions to tightly folded protein domains and their effects on Yersinia enterocolitica type III secretion

被引：43

作者：

Lee, VT ^{[1
]}

Schneewind, O ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USA

来源：

JOURNAL OF BACTERIOLOGY | 2002年 / 184卷 / 13期

关键词：

D O I：

10.1128/JB.184.13.3740-3745.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Yersinia enterocolitica organisms secrete Yop proteins via the type III pathway. Translational fusion of yop genes to ubiquitin or dihydrofolate reductase results in hybrid proteins that cannot be secreted. The folding of hybrids prevents their own transport, but it does not hinder the type III secretion of other Yops.

引用

页码：3740 / 3745

页数：6

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