Homeostatic expansion versus antigen-driven proliferation: common ends by different means?

被引：32

作者：

Prlic, M ^{[1
]}

Jameson, SC ^{[1
]}

机构：

[1] Univ Minnesota, Dept Lab Med & Pathol, Ctr Immunol, Minneapolis, MN 55455 USA

来源：

MICROBES AND INFECTION | 2002年 / 4卷 / 05期

关键词：

T cell; homeostasis; proliferation; expansion; lymphopenia; cytokine; costimulation; survival;

D O I：

10.1016/S1286-4579(02)01569-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The requirements for T-cell proliferation driven by "space-filling" (homeostatic expansion) differ significantly from those for antigen-driven responses. Here we review these differences and discuss their implications for regulation of T-cell responses and the size of the T-cell compartment. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：531 / 537

页数：7

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