The genome of the natural genetic engineer Agrobacterium tumefaciens C58

被引：628

作者：

Wood, DW

Setubal, JC

Kaul, R

Monks, DE

Kitajima, JP

Okura, VK

Zhou, Y

Chen, L

Wood, GE

Almeida, NF

Woo, L

Chen, YC

Paulsen, IT

Eisen, JA

Karp, PD

Bovee, D

Chapman, P

Clendenning, J

Deatherage, G

Gillet, W

Grant, C

Kutyavin, T

Levy, R

Li, MJ

McClelland, E

Palmieri, A

Raymond, C

Rouse, G

Saenphimmachak, C

Wu, ZN

Romero, P

Gordon, D

Zhang, SP

Yoo, HY

Tao, YM

Biddle, P

Jung, M

Krespan, W

Perry, M

Gordon-Kamm, B

Liao, L

Kim, S

Hendrick, C

Zhao, ZY

Dolan, M

Chumley, F

Tingey, SV

Tomb, JF

Gordon, MP

Olson, MV

机构：

[1] Univ Washington, Dept Microbiol, Seattle, WA 98195 USA

[2] Univ Estadual Campinas, CBMEG, BR-13083970 Campinas, SP, Brazil

[3] Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA

[4] Univ Washington, Genome Ctr, Seattle, WA 98195 USA

[5] Univ Fed Mato Grosso, Dept Comp & Stat, BR-79070900 Campo Grande, MS, Brazil

[6] Inst Genome Res, Rockville, MD 20850 USA

[7] SRI Int, Bioinformat Res Grp, Menlo Pk, CA 94025 USA

[8] Univ Washington, Howard Hughes Med Inst, Seattle, WA 98195 USA

[9] Dupont Co Inc, Newark, DE 19714 USA

[10] Pioneer HiBred Int Inc, Johnston, IA 50131 USA

[11] Univ Washington, Dept Biochem, Seattle, WA 98195 USA

[12] Univ Washington, Dept Bot, Seattle, WA 98195 USA

来源：

SCIENCE | 2001年 / 294卷 / 5550期

关键词：

D O I：

10.1126/science.1066804

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The 5.67-megabase genome of the plant pathogen Agrobacterium tumefaciens C58 consists of a circular chromosome, a linear chromosome, and two plasmids. Extensive orthology and nucleotide colinearity between the genomes of A. tumefaciens and the plant symbiont Sinorhizobium meliloti suggest a recent evolutionary divergence. Their similarities include metabolic, transport, and regulatory systems that promote survival in the highly competitive rhizosphere; differences are apparent in their genome structure and virulence gene complement. Availability of the A. tumefaciens sequence will facilitate investigations into the molecular basis of pathogenesis and the evolutionary divergence of pathogenic and symbiotic lifestyles.

引用

页码：2317 / 2323

页数：9

共 50 条

[1] PRESENCE OF ONE LINEAR AND ONE CIRCULAR CHROMOSOME IN THE AGROBACTERIUM-TUMEFACIENS C58 GENOME [J].